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How regular Aspirin could reduce liver cancer risk

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Researchers at Massachusetts General Hospital have found that regular aspirin use can reduce the risk of developing liver cancer.
The findings — which appear in JAMA Oncology— support the results of prior studies on the same topic.Data from this report show that taking aspirin on a regular basis can lower the risk of developing liver cancer, or hepatocellular carcinoma (HCC). IMG-20180912-WA0030The scientists defined “a regular basis” as taking two or more 325-milligram tablets per week for 5 years or more.

The study’s results are promising. “Regular use of aspirin led to significantly lower risk of developing HCC, compared to infrequent or no aspirin use, and we also found that the risk declined progressively with increasing aspirin dose and duration of use,” says lead author Dr. Tracey Simon, who is a research fellow from the Massachusetts General Hospital Division of Gastroenterology in Boston.

Reopening the data

The researchers looked over data, including health information on more than 170,000 people, that were collected for over 3 decades.

One part of the questionnaire these patients filled out was whether they took aspirin, how often they took it, and for how long. Another part of the data included liver cancer diagnosis.

When the scientists had analyzed the numbers, they revealed that people who took two (or more) 325-milligram doses of aspirin each week had a 49 percent reduction in their risk of developing liver cancer.

For those who took aspirin for 5 years (or more), that risk was reduced by 59 percent.

 Also, the team saw that the risk reduction decreased if the participant stopped taking aspirin and disappeared entirely 8 years after they stopped taking aspirin. There was no decrease in risk of liver cancer when participants took acetaminophen or ibuprofen.



The facts on liver cancer

Liver cancer is not a particularly common type of cancer, but it has been on the rise over the past few decades. Someone’s risk of developing liver cancer is elevated if they already have liver disease, such as hepatitis B or hepatitis C.

If somebody has cirrhosis of the liver — which is when scar tissue replaces normal liver cells and prevents the liver from working as it should — their risk of liver cancer is also elevated.

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Liver cancer is now the third leading cause of cancer deaths around the world. Some signs and symptoms include:

  • a hard lump just below the rib cage on the right side
  • discomfort in that same area
  • a swollen abdomen
  • pain in the right shoulder blade or back
  • jaundice (a yellow discoloration of the skin and whites of the eyes)
  • bruising or bleeding more easily
 If a person experiences unintentional weight loss, nausea and vomiting, loss of appetite, and unusual tiredness or weakness, they should contact their doctor.
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24 Hours Across Africa

Tanzania: officials summons WHO over Ebola claims

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Tanzania’s government has summoned the World Health Organisation’s local representative over claims that they’re concealing information on Ebola virus infections in the country.

On Saturday, WHO said in a statement that it had learned of one suspected fatal case in the main city, Dar es Salaam, and two other infections but, despite repeated requests, was given no information.

Last week, Tanzania said it had no confirmed or suspected cases of Ebola.

Government spokesman Hassan Abbasi said on Twitter that the ministry of foreign affairs had summoned the WHO’s Tigest Ketsela Mengestu to obtain “in-depth details from the agency on reports circulating in the media”.

A short video clip has also been posted on the ministry’s Twitter account, showing Dr Tigest clarifying at a meeting with Deputy Minister for Foreign Affairs Damas Ndumbaro that the WHO did not say there was Ebola in Tanzania:

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WHO rejects claims to issue a statement on existence of Ebola in Tanzania.

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More than 2,100 people have died during the current Ebola outbreak in neighbouring Democratic Republic of Congo.

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WHO accused Tanzania of hiding information on Ebola victims

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Ebola virus has cause major loss of life and socioeconomic disruption in Africa.

The number of cases has began to decline gradually, following the commitment of substantial international resources.

The World Health Organization (WHO) has rebuked Tanzania for failing to provide information about possible Ebola virus infections.

The WHO said it had learned of one suspected fatal case in Dar es Salaam and two others but, despite repeated requests, was given no information

Tanzania has said it has no suspected or confirmed cases.

The latest outbreak has killed more than 2,000 in eastern DR Congo, with Uganda battling to stop any spread.

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