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Sickle cell may get solution soon – scientists.

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Scientists in the U.S. have unveiled results of a small clinical trial that could mean an effective “cure” for sickle cell anemia, the painful and debilitating disease that inflicts many millions of people across the globe, mostly of African heritage and including some 100,000 African Americans in the U.S.



Researchers at the National Institutes of Health (NIH) say they have used gene therapy techniques to add a “corrected” gene for healthy red blood cells into the bodies of nine test patients, replacing their diseased red blood cells caused by sickle cell anemia and effectively ridding them of signs of the disease.

NIH Director Francis Collins described the trial results as seemingly “spectacular”.

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“When you look at their blood counts and their blood smears, it looks like they don’t have it anymore,” Collins said on Monday (March 11) from his office at the NIH in Bethesda, Maryland, just outside Washington, D.C.

Sickle cell disease is an inherited blood disorder that causes protein crystals to form inside red blood cells, changing their shape from a flat disk into a crescent or sickle shape that then clogs up the small blood vessels and results in terrible episodes of pain and organ damage.

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But they believe the basic premise of introducing a corrected gene into the body holds promise for Africa provided a simpler, cheaper and less toxic delivery system than bone marrow transplant and the accompanying chemotherapy can be found.

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24 Hours Across Africa

Zimbawe’s doctor goes missing after masterminding strike

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Fearless Zimbabwe’s minister of health has called on the government to address insecurity lapses that has lead to the disappearance Peter Magombeyi, the head of a doctor’s union, who disappeared on Saturday.

Fears are rising over the fate of Zimbabwe medical doctor Dr Peter Magombeyi after he sent a message to say he had been abducted in that country by unknown persons – apparently for demanding a “living wage”.

An AFP report earlier on Sunday quoted the Zimbabwe Hospital Doctor’s Association (ZHDA) as saying Magombeyi had not been heard from since he sent a WhatsApp message on Saturday night saying he had been “kidnapped by three men”.

Zimbabwe doctors, who earn a miserly equivalent of about R3 000 are on strike to press for better wages, equipment and medicines in state hospitals.

The ZHDA has reportedly accused state security forces of abducting the doctor because of his role in organising work stoppages.

This week some doctors said the death of deposed Robert Mugabe, 95, in a Singapore hospital on 6 September was an indication of how bad health services in Zimbabwe

“Dr Magombeyi’s crime is only to ask for a living wage for his profession. This is a reflection of the troubles born out of refusal to implement Political Reforms.”

The Zimbabwe government led by Emmerson Mnangagwa has not publicly commented on the doctor’s disappearance

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24 Hours Across Africa

Turkey: Group calls for immediate action against Femicide

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Emine Dirican, a beautician from Istanbul, tried to be a good wife. But her husband hated that she worked, that she socialized, even that she wanted to leave the house sometimes without him.

She tried to reason with him. He lashed out.

“One time, he tied me — my hands, my legs from the back, like you do to animals,” recalls Dirican, shuddering. “He beat me with a belt and said, ‘You’re going to listen to me, you’re going to obey whatever I say to you.’ “

She left him and moved in with her parents. In January, he showed up, full of remorse and insisting he had changed. She let him in.

In her mother’s kitchen, he grabbed her by the hair, threw her to the floor and pulled out a gun.

“He shot me,” she says. “Then he went back to my mom and he pulled the trigger again, but the gun was stuck. So he hit her head with the back of the gun.”

Her father, who was in another room in the house, heard the gunshots and ran over. Dirican almost bled to death after a bullet ripped through a main artery in one of her legs.

“I was telling my father, ‘Daddy, please, I don’t want to die.’ “

Femicide — killing women because of their gender — is a longstanding issue in Turkey. Nearly 300 women have been killed so far this year, according to the Istanbul-based advocacy group We Will Stop Femicide, which has been tracking gender-related deaths since Turkish authorities stopped doing so in 2009.

Source Npr news

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